ADC TOXICITY ATLAS
Targets
Target

c-MET (HGFR)

Gene
MET
Receptor tyrosine kinase
UniProt · P08581ADCdb · TAR0AIJKM
Target expression

Eye-tissue expression

Cornea · central
26.59 %
Cornea · limbal
37.08 %
Conjunctiva
67.14 %
RPE
59.48 %
Retina · HPA
3.6 nTPM
Computed · Human Cell Atlas (scRNA detection) & HPA bulk RNA - how this is computed →
3 agents

ADCs against this target

Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
MYTX-011MMAE
47
33
0
0
5
36
36
Telisotuzumab vedotinMMAE
25
41
10
14
35
15
10
51
BYON-3521seco-DUBA (duocarmycin)
0
29
3.2
0%severity100%
0
Assessed · clear
true 0%
No data
never assessed