ADC TOXICITY ATLAS
Targets
Target

CD70

Gene
CD70
Other
UniProt · P32970ADCdb · PATR0CXRBX
Target expression

Eye-tissue expression

Cornea · central
0.82 %
Cornea · limbal
1 %
Conjunctiva
0.64 %
RPE
-
Retina · HPA
0 nTPM
Computed · Human Cell Atlas (scRNA detection) & HPA bulk RNA - how this is computed →
2 agents

ADCs against this target

Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
Vorsetuzumab mafodotinCys-mcMMAF
57
26
30
ARX-305AS269 (Amberstatin 269) - monomethyl auristatin F (MMAF) derivative
46.3
58.5
29.3
43.9
0%severity100%
0
Assessed · clear
true 0%
No data
never assessed