ADC TOXICITY ATLAS
AtlasPayloads and LinkersPayloadsTargetsMethods
← Targets
Target

Trophoblast glycoprotein (5T4)

Gene
TPBG
Other
UniProt · Q13641 ↗ADCdb · TAR0XFYLU ↗
Target expression

Eye-tissue expression

Cornea · central
-
Cornea · limbal
-
Conjunctiva
-
RPE
-
Retina · HPA
-
Computed · Human Cell Atlas (scRNA detection) & HPA bulk RNA - how this is computed →
2 agents

ADCs against this target

Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
PF-06263507MMAF (monomethyl auristatin F)
38.5
11.5
23.1
7.7
23.1
7.7
JK-06MMAE
10
10
0%severity100%
0
Assessed · clear
true 0%
No data
never assessed