ADC TOXICITY ATLAS
AtlasPayloads and LinkersPayloadsTargetsMethods
← Targets
Target

NaPi2b (sodium-dependent phosphate transport protein 2B / NaPi-IIb)

Gene
SLC34A2
SLC transporter
UniProt · O95436 ↗ADCdb · TAR0AABNG ↗
Target expression

Eye-tissue expression

Cornea · central
-
Cornea · limbal
-
Conjunctiva
-
RPE
-
Retina · HPA
-
Computed · Human Cell Atlas (scRNA detection) & HPA bulk RNA - how this is computed →
2 agents

ADCs against this target

Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
Upifitamab rilsodotinAuristatin F-HPA (AF-HPA)
41
69
49.6
39.2
51.9
9.6
Lifastuzumab vedotinMMAE
20
22
73
61
32
49
34
61
0%severity100%
0
Assessed · clear
true 0%
No data
never assessed