ADC TOXICITY ATLAS
Atlas
Payloads and Linkers
Payloads
Targets
Methods
← Targets
Target
ROR1
Gene
ROR1
Receptor tyrosine kinase
UniProt · Q01973 ↗
ADCdb · TAR0LTTSS ↗
Target expression
Eye-tissue expression
Cornea · central
1.09
%
Cornea · limbal
3.42
%
Conjunctiva
4.09
%
RPE
-
Retina · HPA
-
Computed · Human Cell Atlas (scRNA detection) & HPA bulk RNA - how this is computed →
1 agent
ADCs against this target
Any-grade
Grade 3+
Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
Zilovertamab vedotin
MMAE
0
23
31.4
13
27.5
48
0%
severity
100%
0
Assessed · clear
true 0%
No data
never assessed