ADC TOXICITY ATLAS
AtlasPayloads and LinkersPayloadsTargetsMethods
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Target

CA6 sialoglycotope (MUC1-associated tumor carbohydrate antigen) -- NOTE: not carbonic anhydrase 6

Gene
MUC1 (CA6 epitope carried on MUC1)
Mucin
UniProt · P15941 ↗ADCdb · TAR0VNYPU ↗
Target expression

Eye-tissue expression

Cornea · central
-
Cornea · limbal
-
Conjunctiva
-
RPE
-
Retina · HPA
-
Computed · Human Cell Atlas (scRNA detection) & HPA bulk RNA - how this is computed →
1 agent

ADCs against this target

Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
SAR-566658DM4 (ravtansine)
36
0%severity100%
0
Assessed · clear
true 0%
No data
never assessed