ADC TOXICITY ATLAS
Targets
Target

Lymphocyte antigen 6E (LY6E)

Gene
LY6E
GPI-anchored
UniProt · Q16553ADCdb · TAR0LXDND
Target expression

Eye-tissue expression

Cornea · central
-
Cornea · limbal
-
Conjunctiva
-
RPE
-
Retina · HPA
-
Computed · Human Cell Atlas (scRNA detection) & HPA bulk RNA - how this is computed →
1 agent

ADCs against this target

Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
DLYE5953A (RG-7841)MMAE
10
16
13
12
38
35
0%severity100%
0
Assessed · clear
true 0%
No data
never assessed