ADC TOXICITY ATLAS
Atlas
Payloads and Linkers
Payloads
Targets
Methods
← Targets
Target
LRRC15 (leucine-rich repeat-containing protein 15)
Gene
LRRC15
Other
UniProt · Q8TF66 ↗
ADCdb · TAR0QEXPC ↗
Target expression
Eye-tissue expression
Cornea · central
-
Cornea · limbal
-
Conjunctiva
-
RPE
-
Retina · HPA
-
Computed · Human Cell Atlas (scRNA detection) & HPA bulk RNA - how this is computed →
1 agent
ADCs against this target
Any-grade
Grade 3+
Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
Samrotamab vedotin (ABBV-085)
MMAE
24.4
19
31
0%
severity
100%
0
Assessed · clear
true 0%
No data
never assessed