ADC TOXICITY ATLAS
Atlas
Payloads and Linkers
Payloads
Targets
Methods
← Targets
Target
GPNMB
Gene
GPNMB
Other
UniProt · Q14956 ↗
ADCdb · TAR0MCXEX ↗
Target expression
Eye-tissue expression
Cornea · central
1.48
%
Cornea · limbal
11.06
%
Conjunctiva
49.3
%
RPE
-
Retina · HPA
-
Computed · Human Cell Atlas (scRNA detection) & HPA bulk RNA - how this is computed →
1 agent
ADCs against this target
Any-grade
Grade 3+
Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
Glembatumumab vedotin
MMAE
0
11.7
39.4
16.9
44.1
36.2
0%
severity
100%
0
Assessed · clear
true 0%
No data
never assessed