ADC TOXICITY ATLAS
AtlasPayloads and LinkersPayloadsTargetsMethods
← Targets
Target

Folate receptor alpha

Gene
FOLR1
GPI-anchored
UniProt · P15328 ↗ADCdb · TAR0QHAVI ↗
Target expression

Eye-tissue expression

Cornea · central
0.02 %
Cornea · limbal
0.07 %
Conjunctiva
0.19 %
RPE
3.21 %
Retina · HPA
0.4 nTPM
Computed · Human Cell Atlas (scRNA detection) & HPA bulk RNA - how this is computed →
5 agents

ADCs against this target

Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
Mirvetuximab soravtansineDM4 (free)
59
57
22
17
18
29
10
36
Farletuzumab ecteribulinEribulin
9
20.8
45
27
33.3
23
6.7
Farletuzumab (naked Ab)N/A (naked antibody)
0
25
51
33.3
42.4
16
19.6
Rinatabart sesutecanExatecan
0
70
0
0
BAT-8006Exatecan
0
37
0
0%severity100%
0
Assessed · clear
true 0%
No data
never assessed