ADC TOXICITY ATLAS
Atlas
Payloads and Linkers
Payloads
Targets
Query
Methods
← Targets
Target
FGFR2
Gene
FGFR2
Receptor tyrosine kinase
UniProt · P21802 ↗
ADCdb · TAR0OXEAL ↗
Target expression
Eye-tissue expression
Cornea · central
58.38
%
Cornea · limbal
77.56
%
Conjunctiva
74.29
%
RPE
-
Retina · HPA
0.7
nTPM
Computed · Human Cell Atlas (scRNA detection) & HPA bulk RNA - how this is computed →
1 agent
ADCs against this target
Any-grade
Grade 3+
Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
Aprutumab ixadotin
Auristatin W
40
60
10
50
30
25
0%
severity
100%
0
Assessed · clear
true 0%
No data
never assessed