ADC TOXICITY ATLAS
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Target

Claudin-18.2 (CLDN18.2 isoform)

Gene
CLDN18
Claudin / tight-junction
UniProt · P56856 ↗ADCdb · TAR0IBZAS ↗
Target expression

Eye-tissue expression

Cornea · central
-
Cornea · limbal
-
Conjunctiva
-
RPE
-
Retina · HPA
-
Computed · Human Cell Atlas (scRNA detection) & HPA bulk RNA - how this is computed →
3 agents

ADCs against this target

Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
SYSA-1801Monomethyl auristatin E (MMAE)
21.2
XNW-27011YL0010014
0
67.9
59.5
0
0
ATG-022Monomethyl auristatin E (MMAE)
0
10.8
37.8
37.8
0%severity100%
0
Assessed · clear
true 0%
No data
never assessed