ADC TOXICITY ATLAS
Targets
Target

Membrane cofactor protein (CD46)

Gene
CD46
Other
UniProt · P15529ADCdb · TAR0JMGXV
Target expression

Eye-tissue expression

Cornea · central
-
Cornea · limbal
-
Conjunctiva
-
RPE
-
Retina · HPA
-
Computed · Human Cell Atlas (scRNA detection) & HPA bulk RNA - how this is computed →
1 agent

ADCs against this target

Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
FOR-46Monomethyl auristatin E (MMAE)
0
21
70
30
39
45
0%severity100%
0
Assessed · clear
true 0%
No data
never assessed