ADC TOXICITY ATLAS
AtlasPayloads and LinkersPayloadsTargetsMethods
← Targets
Target

B7-H3 (CD276)

Gene
CD276
Immunoglobulin superfamily
UniProt · Q5ZPR3 ↗ADCdb · TAR0RIOXT ↗
Target expression

Eye-tissue expression

Cornea · central
-
Cornea · limbal
-
Conjunctiva
-
RPE
-
Retina · HPA
-
Computed · Human Cell Atlas (scRNA detection) & HPA bulk RNA - how this is computed →
1 agent

ADCs against this target

Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
Vobramitamab duocarmazineseco-DUBA (duocarmazine)
19.8
5.8
25.6
14
26.7
30.2
2.3
4.7
0%severity100%
0
Assessed · clear
true 0%
No data
never assessed