ADC TOXICITY ATLAS
AtlasPayloads and LinkersPayloadsTargetsMethods
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Target

Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9)

Gene
ADAM9
Receptor tyrosine kinase
UniProt · Q13443 ↗ADCdb · TAR0DMCMD ↗
Target expression

Eye-tissue expression

Cornea · central
-
Cornea · limbal
-
Conjunctiva
-
RPE
-
Retina · HPA
-
Computed · Human Cell Atlas (scRNA detection) & HPA bulk RNA - how this is computed →
1 agent

ADCs against this target

Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
IMGC-936DM21 (linker-payload DM21-C)
77.8
7.7
0
10
38.5
23.1
15.4
0
0%severity100%
0
Assessed · clear
true 0%
No data
never assessed