ADC TOXICITY ATLAS
Payloads & linkers
Linker · Cleavable

β-glucuronide + PAB

Cleavable

structure not applicable
Physicochemistry

Properties

MW
-
TPSA
-
xLogP
-
Formula
-
Cleavage
Cleavable
Attachment
Site-specific (enzymatic/non-natural AA)
1 agent

ADCs built on this linker

Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
FS-1502ERBB2
55.3
66.7
34
26.7
33.3
3.3
0%severity100%
0
Assessed · clear
true 0%
No data
never assessed