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Linker

AS269 non-cleavable oxime (pAcF)

Non-cleavable

NOCCOCCOCCOCCO
Physicochemistry

Properties

MW
209.242 Da
TPSA
83.17 Ų
xLogP
-1.0812
Formula
C8H19NO5
Cleavage
Non-cleavable
Attachment
Site-specific (enzymatic/non-natural AA)
1 agent

ADCs built on this linker

Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
ARX788ERBB2
46.4
70.9
23.3
36.7
25
20
34.8
0%severity100%
0
Assessed · clear
true 0%
No data
never assessed