ADC TOXICITY ATLAS
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Linker

Lys non-cleavable (auristatin W)

Non-cleavable

CCCCCC(=O)O
Physicochemistry

Properties

MW
116.16 Da
TPSA
37.3 Ų
xLogP
1.6513
Formula
C6H12O2
Cleavage
Non-cleavable
Attachment
Lysine
1 agent

ADCs built on this linker

Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
Aprutumab ixadotinFGFR2
40
60
50
30
25
0%severity100%
0
Assessed · clear
true 0%
No data
never assessed