ADC TOXICITY ATLAS
Payloads & linkers
Linker

Pip-Val-Cit

Cleavable

CC(C)[C@H](NC(=O)CCC(=O)N1CCC(C(N)=O)CC1)C(=O)N[C@@H](CCCNC(N)=O)C(=O)O
Physicochemistry

Properties

MW
484.554 Da
TPSA
214.02 Ų
xLogP
-1.3508
Formula
C21H36N6O7
Cleavage
Cleavable
Attachment
-
1 agent

ADCs built on this linker

Agent · target
Ocular
Hepatic
Neutrop.
Thrombo.
Anemia
GI
ILD
Neuro.
ZV0203ERBB2
60
40
26.7
26.7
0
0%severity100%
0
Assessed · clear
true 0%
No data
never assessed